Arrays of dielectric elastomer microactuators for cell mechanotransduction
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Eurosensors XXV , September 4 - 7 , 2011 , Athens , Greece Arrays of 100 μ m x 100 μ m dielectric elastomer actuators to strain the single cells
Dielectric Elastomer Actuators (DEA) are compliant devices capable of generating large percentage strains with sub-second response times. Miniaturizing DEAs is challenging principally because of the need for μm-scale compliant electrodes. Employing low-energy gold-ion implantation into a 30 μm thick membrane of Polydimethylsiloxane (PDMS), we have patterned 100 μm wide compliant electrodes and ...
متن کاملMicrofabrication and characterization of an array of dielectric elastomer actuators generating uniaxial strain to stretch individual cells
Cells regulate their behavior in response to mechanical strains. Cell cultures to study mechanotransuction are typically cm2 in area, far too large to monitor single cell response. We have developed an array of dielectric elastomer microactuators as a tool to study mechanotransduction of individual cells. The array consists of 72 100 μm × 200 μm electroactive polymer actuators which expand unia...
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A key element in stretchable actuators, sensors, and systems based on elastomer materials are compliant electrodes. While there exist many methodologies for fabricating electrodes on dielectric elastomers, very few succeed in achieving high-resolution patterning over large areas. We present a novel approach for the production of mechanically robust, high-resolution compliant electrodes for stre...
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Biological cells modulate their behavior, express genes, proliferate or differentiate in response to mechanical strains ranging from 1% to 20%. There currently exists no technique to apply strain to many targeted individual cells in a larger culture in order to perform parallelized high throughput testing. Dielectric elastomer actuators (DEAs) are compliant devices capable of generating large p...
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